Trachoma and the etiology of jequirity ophthalmia / by J. A. Andrews.

  • Andrews, Joseph Andrew.
Date:
[1884]
Catalogue details

Licence: Public Domain Mark

Credit: Trachoma and the etiology of jequirity ophthalmia / by J. A. Andrews. Source: Wellcome Collection.

Provider: This material has been provided by UCL Library Services. The original may be consulted at UCL (University College London)

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    scribed arrangement of lymphoid cells, as represented in fig. I,' and is then without a limiting membrane. The tissue between the foci of infiltration may be quite normal, or, at most, slightly hyperaemic. As a rule, at an early period of their existence the foci of infiltration have a round contour, and the cells at the periphery are smaller and more closely packed together than in the interior, but there is as yet no true anatomical boundary. Under suffi- cient power, the interior of the young follicle has a distinct reticulum. It is a framework consisting of abundantly branching pale fibres with gangliform swellings, and in places stellate, branching points with pale, oval nuclei. At this early stage, therefore, the follicle has an envelope only in the sense that the cells are most closely aggregated at the periphery. At a later period the small cells at the boundary assume an oblong shape, and look like a string of beads; and finally the fibrous boundary of the follicle is formed by the cells at the periphery being drawn out into fibres; however, this fibrous boundary is not always found symmetrically developed, but some part of the circumfer- ence is bridged over with small round cells, and frequently the follicle is found to communicate with the surface of the conjunctiva through a breach in the enveloping capsule. The young follicle represents a pretty solid nodule, and cannot be easily emptied of its contents by puncture from the conjunctival surface. Leber,' on the contrary, main- tains the opposite view. As the disease advances, the fate of the follicle will be varied according to the intensity of the inflammation, and its contents may become obliterated or undergo softening. Frequently the follicles are confluent, and when this con- ^ I am unable to furnish the wood-cut in time for the printers, but on page 31 of GrjEfe and Ssemisch's Handbuch, vol. iv., will be found a similar picture. * Rsehlmann : Grcefe's Archiv, Bd. xxix., 2. plate v., fig. 13; also Jacob- son, Jr.: Ibid., Bd. xxv., 2, p. 169, plate v., fig. 7. •Leber: Bericht der Ophthal. Gesellschaft, Heidelberg, 1878, d. 12.