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Drosophila embryo polarity - role of bicoid gene

  • Dr Daniel St. Johnston
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An illustration of the role of the bicoid gene in the development of polarity in a Drosophila embryo. bicoid mRNA locates to the anterior pole of the developing oocyte. The protein Staufen is required for the microtubule-dependent localisation of bicoid mRNA. Here, fluorescent bicoid mRNA (green) injected into a Drosophila embryo recuits GFP-Staufen (Green) into large particles, which will then localise on the mitotic spindles. The yellow is an area of colocalisation of bicoid mRNA and GFP-Staufen.

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