Sickle cell disease: bone marrow expansion

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Sickle cell disease: bone marrow expansion. Wellcome Collection. CC0 1.0 Universal. Source: Wellcome Collection.

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This is a longitudinal section of an adult femur. Note the active red haemopoietic bone marrow (hyperplasia) throughout the upper femur. There is also a pale area of infarction which is related to a sickle crisis.

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