Genetic recombination : understanding the mechanisms / Harold L.K. Whitehouse.

  • Whitehouse, H. L. K. (Harold L. K.)
Date:
[1982], ©1982
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Licence: Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)

Credit: Genetic recombination : understanding the mechanisms / Harold L.K. Whitehouse. Source: Wellcome Collection.

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    frenetic Understanding the Mechanisms Harold L.K.WhitehoUse Genetic recombination seems to be of universal occurrence in living organisms. Know ledge of its mechanism is of basic importance because it is the process by which segments of corresponding chromosorrfes of paternal and maternal origin are exchanged. Thus, knowledge of the molecular basis of heredity, and of how that molecular structure allows exchanges to occur, underlie any understanding of the process. The widest survey yet produced on this subject, the boqlc describes all the main dis coveries and the evidence on which the conclusions that h^ve : i)een drawn from them are based. This-has involved consideration of bacteria and their viruses as \yell as fungi and other higher organisms, ft is only by placing alongside one another.the molecular data obtained mainly from lower organisms, and the genetical data, more particularly from higher organisms, that a full picture emerges of the current state of knowledge The rapidly advancing field of non-homologous recombination, which differs funda mentally from the ‘normal’ mechanism in not requiring correspondence of nucleotide sequence, is described in the final chapter. Geneticists, molecular biologists, microbiologists, bacteriologists, virologists, and biochemists will find this book invaluable. s < CONTENTS Preface * * f ; c i Introduction - . Genetic transformation Recombination in single-stranded DNA phages of Escherichia coli ]&d l combi.^#on in phage T4 «Rectfrrrbiiiatidn'in eukaryotes Cjr^nercil conclu^iorfS Non-horffologous Vecpm'bination by transpo^afiLe elements « *+*++■** • / JOHN WILEY & SONS Chichester • New York • A Wiley-Interscience Publi , ISBN 0 471 10205 9 if/