Further experiments and observations on the action of poisons on the animal system / by B.C. Brodie.

  • Brodie, Benjamin, Sir, 1783-1862.
Date:
1812
Catalogue details

Licence: Public Domain Mark

Credit: Further experiments and observations on the action of poisons on the animal system / by B.C. Brodie. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    was found that by means of the Voltaic battery powerful con- tractions might be excited, not only of the voluntary muscles, but also of the heart and intestines; from which it may be inferred, that the muriate of barytes, like arsenic, affects the circulation by rendering the heart insensible to the stimulus of the blood, and not by destroying altogether the power of muscular contraction. The muriate of barytes affects the stomach, but in a less degree than arsenic. It operates as an emetic in animals that are capable of vomiting; but sooner when taken internally, than when applied to a wound. In general, but not constantly, there are marks of inflammation of the inner membrane of the stomach, but not of the intestine. In manv instances there is a thin layer of dark coloured coagulum of blood lining the whole inner surface of the stomach and adhering very closely to it, so as to have a good deal of the appearance of a slough; and this is independent of vomiting, as where I met with it, it occurred in rabbits. The same circumstances, from which it may be inferred that arsenic does not produce its deleterious effects until it has passed into the same circulation, lead^ to the same conclusion with regard to the muriate of barytes. V. On the Effects of the Emetic Tartar. The effects of the emetic tartar so much resemble those of arsenic and of muriate of barytes in essential circumstances, that it would be needless to enter into a detail of the individual experiments made with this poison. W hen applied to a wound in animals, which are capable of vomiting, it usually, but not constantly, operates very speedily