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Gastrointestinal hormones.

  • Gillespie, Iain E.
  • Videos
  • Online

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Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
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About this work


Professor Iain Gillespie lectures on the hormones of the gastrointestinal tract. He describes how this field of study is relatively new because previously it was not thought that there were hormones secreted directly from the gastrointestines. In his lecture, he concentrates on the three main hormones: gastrin, secretin and cholecystokinin (CCK). He describes the function of each and discusses their pharmacological actions in diagnosis or treatment of gastrointestinal disease.


London : University of London Audio-Visual Centre, 1976.

Physical description

1 encoded moving image (27.23 min.) : sound, black and white.



Copyright note

University of London

Terms of use

Creative Commons Attribution-Non-Commercial 2.0 UK: England & Wales

Language note

In English

Creator/production credits

Presented by Professor Iain Gillespie, University of Manchester. Introduced by Dr Ian Gilliland. Produced by Peter Bowen. Made for British Postgraduate Medical Federation. Made by University of London Audio-Visual Centre.


This video is one of around 310 titles, originally broadcast on Channel 7 of the ILEA closed-circuit television network, given to Wellcome Trust from the University of London Audio-Visual Centre shortly after it closed in the late 1980s. Although some of these programmes might now seem rather out-dated, they probably represent the largest and most diversified body of medical video produced in any British university at this time, and give a comprehensive and fascinating view of the state of medical and surgical research and practice in the 1970s and 1980s, thus constituting a contemporary medical-historical archive of great interest. The lectures mostly take place in a small and intimate studio setting and are often face-to-face. The lecturers use a wide variety of resources to illustrate their points, including film clips, slides, graphs, animated diagrams, charts and tables as well as 3-dimensional models and display boards with movable pieces. Some of the lecturers are telegenic while some are clearly less comfortable about being recorded; all are experts in their field and show great enthusiasm to share both the latest research and the historical context of their specialist areas.


Segment 1 Dr Ian Gilliland introduces Professor Iain Gillespie. Gillespie begins by saying that gastrointestinal hormones have recently 'gained respectability' in the world of endocrinology as previously it was not known that they actually existed. He introduces and describes the three hormones his lecture will feature: gastrin, secretin and cholecystokinin (CCK). Time start: 00:00:00:00 Time end: 00:04:09:00 Length: 00:04:09:00
Segment 2 Gillespie uses a table with moveable pieces to illustrate his points about the structure of the hormone gastrin. He refers then to a graph which shows gastrin levels in different disorders of the stomach. Attention is paid to the vagus nerve and its role in the development of gastric ulcers; he describes surgery to remove the vagus (vagotomy) and drugs which suppress its stimulation of gastrin. Time start: 00:04:09:00 Time end: 00:10:45:00 Length: 00:06:39:00
Segment 3 Gillespie shows a graph which measures levels of pentagastrin before and after vagotomy in patients with duodenal ulcers. He them moves on to look at secretions other than acid that are induced by gastrin. He refers to an illustration of the gastrointestinal tract. Time start: 00:10:45:00 Time end: 00:15:44:00 Length: 00:04:59:00
Segment 4 Gillespie moves on to discuss the hormone, secretin. He shows an illustration of its amino acid sequence, then uses graphs and diagrams relating to the effects of secretin on the body. After this, he discusses CCK and its effects on the body, particularly its relationship to smooth muscle tissue. Time start: 00:15:44:00 Time end: 00:20:53:00 Length: 00:05:09:00
Segment 5 Gillespie now brings all the threads of his lecture together and discusses the interactions between the hormones which has has previouly referred to separately. He describes studies in which the hormones are combined in different ways. He ends the lecture by looking forward to future research into the area. Time start: 00:20:53:00 Time end: 00:27:23:13 Length: 00:06:30:13


  • English

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