The crescent forms of the erythrocyte in normal and pathologic blood expressions : origin of red blood corpuscle and blood plasm / by Frank A. Stahl.

  • Stahl, Frank August, 1862-
Date:
[1887?]
Catalogue details

Licence: Public Domain Mark

Credit: The crescent forms of the erythrocyte in normal and pathologic blood expressions : origin of red blood corpuscle and blood plasm / by Frank A. Stahl. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

    7/26 (page 3)
    STAlll. THE CTiESCENT EOHiMS OF THE EKYTHHOC'YTE. Thus i1 will be seen tliere are three blood eireulations eharae- leri/.iiig the OYUiii; the one following the other; the first two being temporary in duration; the third being the i)ermanent red l)lood eolored cirenlation of the permanent erythroeyte, the erytii- roeyte not being subject to change. They are: 1— The primary uncolored blood eircidation, where the uncol- ored [)rimal blood nucleus-corpuscle is predominant and tem])o- rary; continues to about the 6-8th week. 2— The initial red blood circulation; where the red erythro- blast l)ecomes characteristic and temporary, and lends new red color to the blood circulation; continues beyond the third month. o—The permanent red blood circulation where the mature non-nucleated red blood corpuscle, the erythrocyte becomes char- acteristic and remains so ])ermanently; thus continuing the red color permanently to the blood circulation. As is well known the crescent forms of erythrocyte occur in pathology, especially in the blood diseases of the amemias. In the amemias the crescents are easily recognized because of their numbers; they seem not so numerous or easy to find in the normal. 'Phis hesitancy might be explained in that, the normal blood cor- l)uscle ditferentiatioii being uidiindered by a dyscrasia from disea.se of blood or body, with consequent lowering of tone of blood corpuscle differentiation; the normal differentiation, there- fore, is Yigoronsly carried along by a normal 100% blood cor- piLscle differentiation, to completion of and without deformity of blood cell. Whereas in the a)uemias, there is hindrance and l)ackward- ness in differentiation; incompletion in blood cell outline and substance; a slower development in general process and con- tinued metamorphosis; many times there is stasis. Therefore, the greater numbers and more easily recognized blood cell incomple- tion and deformity in pathology; proportionate to lo.ss of physiol- ogy and function in blood cell and stream, there follow debility and death, as sequela;. R('cognition of crescent shaped erythi-ocytes, in mature life, .spells pathology in diagnosis. Two of the.se crescent forms wei-e found in the blood vessels of the chorion of a 7-8th week human ovum; the third in the Area ATisculosa in the same ovum, near the still open free inner margin of the chorion; before fusion of the amnion with the chorion.