The crescent forms of the erythrocyte in normal and pathologic blood expressions : origin of red blood corpuscle and blood plasm / by Frank A. Stahl.

  • Stahl, Frank August, 1862-
Date:
[1887?]
Catalogue details

Licence: Public Domain Mark

Credit: The crescent forms of the erythrocyte in normal and pathologic blood expressions : origin of red blood corpuscle and blood plasm / by Frank A. Stahl. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

    19/26 (page 9)
    STAHL: Till’. (’HLSCKNT FOiniS OF TIIF. FKY'l'llHOt'YTF. }) ing to those oeeurring in normal blood corpiisele differentiation. ()—The nneleated sickle-cell erythrocyte, malformed through ilyscrasia of amemia ; analogue to the normal nneleated crescent erythrocyte, Fig. 1, above. 7—The non-nneleated sickle-cell erythrocyte, malformed, ana- logue to the normal non-nucleated erythrocyte seen in Fig. 3, above. Another of the valued features of this illustration is the pictur- ing of changes in detail of the differentiations; in the disa]>pear- ance of the nucleus from the blood cell in the differentiations, from the nucleated to the non-nucleated erythrocyte; diff'erentia- tion being the same in the normal as in the pathologic. 1— Nucleus of erythroeyte wandered to edge of its cell. 2— Just ready for extrusion of nnchns into general blood stream. 3— Nucleus rests loosely in cell cavity as though moment jnst before casting otf. 4— Peripheral cell cavity as though just emptied of a nucleus. b—Many nnclei-whole-extruded into general blood stream. Finally, the many perfect non-nucleated erythrocytes dissemi- nated throughout the general field. Discussion: In disappearance of nucleus from erythrocyte: .Migration and Extrusion versus Fragmentation and Absorption. In this illustration can also be seen crucial decisions in the now far more mild controversy of Migration and Extrusion of nucleus of erythrocyte versus Fragmentation and Absorption. Here is seen plainly Migration of blood cell lindens to the edge of its cell; then Extrusion of nucleus as a whole into the general blood stream, where undoubtedly Fragmentation occurs; finally Absorption. In the normal, see Fig. 2 aliove. iMay it not be that in the Fragmentation of the nucleus in the stream of the general circulation, into such minute particles as to be until now, unrecognizable to stain and microscope; that in this minute Fragmentation, as invisible nucleoli, that therein may lie the secret and seed of Continuation of Erythrocyte in Mature Life and even in that of Fetal Existence. Fig. 10.—Cross section of blood space-vessel from auIIus 7-8th week; content mono-niicleated erythroblasts; erjdhroblasts in stroma of villus; observe nuclei wandering from second row to- wards the blood vessel, several empty spaces in second row; sev- eral eoarse mnlti-nucleated nuclei in rim of blood vessel; the flat-