Practical observations on the remedial properties of Simaba cedron, and on its employment as a substitute for quinine / by Samuel S. Purple.
- Purple, Samuel S. (Samuel Smith), 1822-1900.
- Date:
- 1854
Licence: Public Domain Mark
Credit: Practical observations on the remedial properties of Simaba cedron, and on its employment as a substitute for quinine / by Samuel S. Purple. Source: Wellcome Collection.
Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.
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![1854.] fourth paroxysm. She was ordered, as there was consider- able gastric derangement, fifteen grains pil. rhei. comp., to be taken immediately; and after the next paroxysm of fever, to take ten grains of the cedron in powder every two hours. At the period of the next (the fifth) paroxysm, she complained of slight headache, but experienced no chill. From this time she was ordered ten grains of cedron, in powder, three times daily, for ten days. She had no return of the disease, and enjoyed, after, her usual health. Case 2.—Mr. B., book-keeper in a bank, aged 27, of spare habit, contracted intermittent fever on Staten Island, in the fall of 18-52, which yielded to quinine. Late in the summer of 1853 he was again the subject of the disease, and con- sulted me some four weeks after the occurrence of the first paroxysm. Belying upon his own judgment, he had already taken quinine, in the same doses as the fall previous, with the effect of temporarily arresting the disease. Its return, after an interval of nine days, led him to resume the use of the quinine in increased doses, until singing of the ears con- vinced him of the propriety of consulting a physician. At the time of his first visit, finding that there existed much tenderness or pressure over the epigastrium, slight yellow- ness of the conjunctiva, and tongue coated with brown fur in the centre, with red tip and edges, he was ordered thirty grains of ipecac, in powder, with ten grains of calomel. This portion operated freely as an emeto-cathartic, and after the succeeding paroxysm of ague, he was ordered ten grains of cedron, reduced to powder by grating the seed on a nutmeg grater, every three hours. The paroxysm of ague, which was expected, at its usual period, was delayed some two hours, and was somewhat less in severity and shorter in du- ration than that which succeeded the action of the emetic. As there existed some pain in the bowels, which' was sup- posed to arise from the action of the cedron, he was ordered the same amount as before, every four hours, combined with fif- teen drops tinct. opii. comp. These directions were steadily adhered to for four days, when the paroxysms of ague hav-](https://iiif.wellcomecollection.org/image/b22435888_0005.jp2/full/800%2C/0/default.jpg)