Bilharziosis / by Frank Cole Madden.

  • Madden, Frank Cole.
Date:
1907
Catalogue details

Licence: In copyright

Credit: Bilharziosis / by Frank Cole Madden. Source: Wellcome Collection.

Provider: This material has been provided by Royal College of Physicians, London. The original may be consulted at Royal College of Physicians, London.

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    formation of bilharzial granulation tissue and its subse- quent transformation into fibrous tissue. The prostate is often found infiltrated, as are also the vesiculae seminales, which, in advanced cases, are almost lost in a fibrous mass, that is welding the base of the bladder to the surrounding connective tissue. There is not usually much enlargement of the prostate, as here the atrophic form of the disease is most commonly found, and contraction, rather than proliferation of the new tissue, is the rule. In later stages, any true pros- tatic symptoms that may be present are masked by the presence of cystitis, stone, etc. Probably the most usual condition of the bladder in severe bilharziosis is as follows:—The bladder in- ternally is thickly infiltrated with extensive patches of dry sandy change, so that portions of the wall are almost entirely converted into a calcified plate; or it is filled with papillomata of various sizes and shapes, very irregularly distributed throughout the mucous membrane. The walls of the bladder are much thickened and infiltrated, and the cavity is considerably contracted. From this thickening and the presence of the papillomatous masses the actual urine space is very small, and the cavity is often eccentrically placed. Owing also to the calcification of the bladder wall the effect of muscular contraction is largely lost, and the bladder is more like a dilatation in a firm-walled tube than a cavity in a contractile organ ” (Milton). The prostate is infiltrated throughout with calcified ova, and may be somewhat enlarged. The urine