On some non-specific reactions of mallein / by H.J. Südemersen and A.T. Glenny.

  • Südmersen, Henry J.
Date:
[1908?]
Catalogue details

Licence: Public Domain Mark

Credit: On some non-specific reactions of mallein / by H.J. Südemersen and A.T. Glenny. Source: Wellcome Collection.

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    over two years. This horse was chosen because at the time it happened to be resting after a period of treatment. The writers were greatly surprised to obtain a large local reaction and a rise of temperature sufficient to condemn the horse (see Chart I). Maltein 0-25cc S.B14 Horse 39* Injected .6 p.m. 12-V-OJ TEMP. °F. At time of injection. After g hours. After 12 hours. After 15 hours. After 18 hours. After 21 hours. 2nd day 3rd day 4th day 105 104 I03 102 roi 100 99 / S / / S / / X X > /- / ✓ r.. / X Temperature °F. 1000 102-6 102-4 101-8 101-6 100-6 100-0 Swelling in Inches * 0 2X3 sharp j’xj' 4’XS slowly decreasing Chart I. First mallein reaction of horse 39K. As the horse was well immunised and produced valuable antitoxin, it was decided to repeat the injection before condemning the animal. A second dose of 2 c.c. mallein (equivalent to twice the former dose) was injected within three days of the first injection. The local swelling produced was more marked than before and the temperature reaction was similar (see Chart II). After both injections of mallein the horse was “ off his food and in low condition.” The reactions obtained were considered sufficient to condemn the horse as glandered, and on May 17th the horse was destroyed. Post-mortem examination was undertaken by Messrs Hunting and Humphrey, Veterinary Inspectors to the London County Council, but no trace of glanders could be found. On the 14th, cultures had been taken directly