Contributions to the physiology and pathology of the breast and its lymphatic glands / by Charles Creighton.

  • Creighton, Charles, 1847-1927.
Date:
1878
Catalogue details

Licence: Public Domain Mark

Credit: Contributions to the physiology and pathology of the breast and its lymphatic glands / by Charles Creighton. Source: Wellcome Collection.

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    the most part to be of the same size as in the state of full development, and the connective tissue separating them was inconsiderable. The acini also were of much the same shape and size as in the secreting gland. But their contents were totally different. While they retained their size and form, their floor, instead of being covered with a mosaic of polyhedric epithelium, presented the following appearances, which were characteristic everywhere of the gland-structure of this animal. It may be stated also that the appearances were the same in various sets of preparations, whether hardened in chromic acid or in methy- lated spirit, and whether coloured with logwood or carmine. Each acinus had strewn over its floor, or arranged at somewhat wide intervals round its margin, a number of deeply-stained cellular bodies of various shapes. Some of them were round, some more or less cubical, a certain number were of a somewhat thick crescentic shape (hemispherical), and others were triangular. Their size corresponded generally to that of an epithelial nucleus, and their substance coloured uniformly throughout. It was at the same time apparent that the floor or circuit of the acinus was also occupied by a number of delicate ring-like forms of a greyish unstained granular appearance, and that the variously shaped Pis. 6. cellular elements were seated on their peri- K phery (Fig. 6). This was most obvious in the ^ C ,^ case of the crescent-shaped coloured masses, for (^') /T^ completed the circuit of which the thin 1^ 1 ^ uncoloured thread formed the larger part. The ^p-v^^ d triangular-shaped bodies were also very signifi- cant • they were found situated below the The contPtits of the ' „ „ , i ^ • „ „ acini in Pip. 5 under point of contact of two such hoops or rings, a powe?5o diameters).^ scoopcd-out sido of tlic triangle forming a part of each circle, and the single triangular body evidently repre- sented the fusion at their opposed surfaces of two independent crescentic bodies. The interpretation to be given of these appearances will be made less doubtful by describing what is found in a somewhat different preparation of which Fig. 7 is a drawing. This is from the udder of a ewe which was said to have been killed a short time after the cessation of the milk. The acini were generally of a large size, and their contents showed several interesting