Cloning issues in reproduction, science and medicine : a consultation document / Human Genetics Advisory Commission and Human Fertilisation & Embryology Authority.

  • Great Britain. Human Genetics Advisory Commission.
Date:
1998
Catalogue details

Licence: Open Government Licence

Credit: Cloning issues in reproduction, science and medicine : a consultation document / Human Genetics Advisory Commission and Human Fertilisation & Embryology Authority. Source: Wellcome Collection.

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    regulations to be made by the Secretary of State for Health before they could be carried out. Further details of the UK’s legal framework are given at Section 5. This paper also discusses whether current science raises new questions about more abstract concepts such as individuality and human dignity. It seeks the views of the community, including specialists drawn from organisations with scientific, legal, clinical or ethical interests. It is envisaged that this paper will be revised in the light of comments received, and form the basis of advice from the HGAC and HFEA to Ministers. Section 2 DOLLY AND POLLY 2.1. Dolly is the first example of an adult vertebrate cloned from another adult by any technique. She was cloned using a nuclear replacement technique, where the nucleus from a cell, which had two chromosome sets, was fused with an unfertilised egg from which the nucleus had been removed. This. experiment was the first time that a fully developed animal had been born following transfer of a somatic cell nucleus from an adult animal. A major motivation for the work was to improve methods for the genetic improvement . of livestock. The technology could also be used to improve the efficiency of production of transgenic livestock. This could have potential benefits, for example, in increasing production of human proteins in the milk of transgenic animals (e.g. proteins used to treat blood clotting disorders such as haemophilia). 2.2 Dolly was the result of a collaborative experiment between the Roslin Institute and PPL Therapeutics PLC to test the suitability of different sources of 4