Clinical examination of the blood and its technique : a manual for students and practitioners / by A. Pappenheim ; translated and adapted from the German by R. Donaldson.

  • Pappenheim, A (Artur), 1870-
Date:
1914
Catalogue details

Licence: In copyright

Credit: Clinical examination of the blood and its technique : a manual for students and practitioners / by A. Pappenheim ; translated and adapted from the German by R. Donaldson. Source: Wellcome Collection.

Provider: This material has been provided by The University of Leeds Library. The original may be consulted at The University of Leeds Library.

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    In the child, the non-granular lymphocytes are increased at the expense of the polynuclear leucocytes. II. PATHOLOGICAL BLOOD. THE RED BLOOD CORPUSCLES. Morphological changes are met with exclusively in conditions of anaemia (invasion of the blood by the parasite of malaria always excepted), and consequently may be looked upon as evidence of the presence of an anaemic syndrome. The majority of anaemias— those of most importance clinically—depend on a haemolytic intoxication caused by venom or by a hving virus. Later, this is coupled with a regenera- tive reaction on the part of the erythroblastic appara- tus of the bone-marrow. Accordingly the morpho- logical changes occurring in erythrocytes fall into two groups, viz. : (i) Degenerative (haemolytic) ; (2) Regenerative (characterized by the presence of young cells). The latest arrivals, viz., the young cell forms, may, on reaching the blood, at once undergo the same toxic degeneration. Hence, not only may degenerated cells and young forms be found side by side in one and the same blood, but not infrequently evidence of both may exist together within one and the same cell (degeneration of the immature forms).* *To these combined types belong, for example, poikilo- cytes showing polychromasia or punctate basophilia, poikilo- cytes with nuclear remains, etc.