Saccharin : the place of saccharin in pharmacy, with formulae / by Professor Attfield.

  • Attfield, John, 1835-1911.
Date:
1889
Catalogue details

Licence: Public Domain Mark

Credit: Saccharin : the place of saccharin in pharmacy, with formulae / by Professor Attfield. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    Take of Soluble Saccharin 30 grains Distilled Water I pint. Dissolve. Each fluid ounce contains a grain and a half of soluble saccharin. Each fluid drachm represents one-sixth of a grain of ordinary saccharin. LIQUOR SACCHARINI, A.P.A. Solution of Saccharin. (From the National Formulary of the American Pharmaceutical Association.) Take of Saccharin ... ... ... ... ... ... ... 512 grains. Bicarbonate of Sodium ... ... ... ... ... 240 grains. Alcohol ... ... ... ... ... 4 fluid ounces. Water, sufficient to produce ... ... ... ... ... 16 fluid ounces. Dissolve. Each fluid drachm represents four gi-ains of saccharin. ELIXIR SACCHARINI, B.P.C.* Elixir of Saccharin. Take of Saccharin ... ... ... ... ... ... ... 480 grains. Bicarbonate of Sodium ... ... ... ... ... 240 grains. Rectified Spirit ... ... ... ... ... ... 2j fluid ounces. Distilled Water ... ... ... ... ... ... a sufficiency. Rub the saccharin and bicarbonate of sodium in a mortar, vrith half a pint of distilled water gradually added. When dissolved, add the spirit, filter, and wash the filter with sufficient distilled water to produce one pint of elixir. Each fluid drachm represents three grains of saccharin. Dose.—5 to 20 minims. Note.—Saccharin itself is but slightly soluble in water (0.46 per cent.), but is readily dissolved if previously mixed with at least half its weight of bicarbonate of sodium, with the sodium of which it forms a soluble saccharinate, containing the equivalent of practically ninety per cent, of saccharin. This is Soluble Saccharin. It is soluble in twice its weight of water. CHEMICAL FORMUL/E. Saccharin. Soluble saccharin. Expressed in weight, 183. Expressed in weight (183—I +23) 205. Or, ICO of saccharin = 112 of soluble saccharin. Or, 100 of soluble saccharin = 895 of saccharin. * The Unofficial Formulary of the British Pharmaceutical Conference.