Serendipity in St. Helena : a genetical and medical study of an isolated community / Ian Shine, with the assistance of Reynold Gold ; and a foreword by Max Rosenheim.

  • Shine, Ian.
Date:
1970
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Licence: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

Credit: Serendipity in St. Helena : a genetical and medical study of an isolated community / Ian Shine, with the assistance of Reynold Gold ; and a foreword by Max Rosenheim. Source: Wellcome Collection.

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    ACKNOWLEDGEMENTS relieved by Dr. J. S. Noaks who generously undertook additional routine duties and so enabled me to devote further time to this study. I would like to thank the Eugenics Society who provided ¿200 for the purchase of books and equipment, the Medical Research Council Population Genetics Research Unit who loaned a transis¬ torized electrocardiogram which was invaluable as the country districts were without electricity, and Professor R. Turner of the Government Pathological Laboratory at Cape Town, who generously donated several litters of mice, analysed samples of water and aqueduct for arsenic, performed histological examination of post¬ mortem material and generously shouldered many of St. Helena's problems. In medical matters I was privileged to have the opportunity to discuss several problems with eminent experts. Advice was given by Dr. J. M. Gullen, Dr. N. J. Bailey and Mr. J. S. Scott; Dr. A. Barr and Miss R. Ash on computing, programming and statistics; Dr. M. Balint on the evil eye; Professor G. Belyavin and Dr. A. Cohen on virology; Dr. Barbara Billing on hyperbilirubinaemia; Dr. Rosemary Biggs and Professor R. G. Macfarlane on blood coagulation who also undertook factor IX assay. Also Professor C. E. Dent, Professor G. Rimmington, Dr. E. B. Dowdle and Dr. E. J. Ross were consulted on metabolic diseases; Dr. J. Gear kindly undertook viral studies; Dr. P.J. Hare, Dr. C. F. H. Vickers and Dr. R. S. Wells gave advice on dermatology; Dr. Catherine Hollman on hallux valgus; Professor J. N. Morris and Dr. W. E. Miall on ischaemic heart disease; Professor Sir George Pickering on arterial disease; Sir Herbert Seddon on orthopaedics; Professor J. M. Tanner on dwarfism; Dr. W. R. Trotter on the thyroid; Professor J. Yudkin on nutrition; and Professor A. W. Woodruff on tropical medicine. I am deeply grateful for their help. I also wish to thank the Royal Air Force for flying blood samples from Ascension Island to England. I am greatly indebted to Dr. A. C. Stevenson for giving me instruction in genetics, generous assistance and much useful criticism of the manuscript. I would like to express my appreciation for the stimulus of Professor N. E. Morton who has made many useful suggestions about the text. The first chapter is based on a book that Dr. R. Gold and I xiv