Acute pemphigus : a contribution to the aetiology of the acute bullous eruptions / by George Pernet and William Bulloch.

  • Pernet, George.
Date:
[1896?]
Catalogue details

Licence: Public Domain Mark

Credit: Acute pemphigus : a contribution to the aetiology of the acute bullous eruptions / by George Pernet and William Bulloch. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    boracic acid lotion. The large bullae wore opened. Boracic acid ointment dressings, then carbolic oil, 1 in 40, were changed as frequently as the condition of the patient would allow. P.M.—I took the opportunity of examining the skin lesions, before proceeding with the actual autopsy. The back, from the nucha to below the gluteal folds, was raw, presenting here and there epithelial sloughs. At the upper part, the raw surface extended from shoulder to shoulder, the width diminishing from above downwards, and corresponding to the parts in contact with the bed in the dorsal decubitus. Beyond the limits of this raw surface there were discrete lesions spreading round the body towards the ventral surface. The flexures of the knees were raw, to the extent of 3i by inches. The elbows were also denuded. The palms were thickened, also the soles of the feet, but to a lesser extent. No trace of an eruption could be seen on these parts. There were no traces of lesions on the ocular conjunctivas. The internal surfaces of the lips were ulcerated, and there were traces of old lesions on the hard palate. On the penis there were two small superficial ulcerations from ^th to ^th inch in diameter about the corona and glans respectively. No enlarged glands could be felt at the elbow and in the axilla on the right side, that is on the same side as the original wound on the little finger. On the legs and feet there were some recent, tense bullae, from about \ to Is inch in diameter, with clear contents. As to the post-mortem examination itself, the following notes were taken:— Twenty-two hours after death, rigor mortis well marked (weather cold and damp). Body well-nourished, of medium but good build. One inch and a half of fat on abdominal wall. A quantity of fat about omentum. Heart and Pericardium.—About half an ounce of fluid in pericardium. Weight of heart, 11) oz. Partially decolorized clot in left ventricle. Slight atheroma of aorta, and slight thickening of aortic valves. Lungs.—Slight band of adhesion about right lung. 'Left lung, no adhesion. No fluid in pleurae. Both lmrgs crepitant all over. Congestion in lower lobe of both lungs. No consolidation. Liver is not obviously enlarged. Surface, smooth. On section, pale, lobules distinct, surrounded by fatty area. Weight, 41bs. 4ozs. Spleen.—5ozs. Apparently slightly enlarged, pultaceous, of light red colour. Kidneys.—Together, 11^ ozs. Capsules, slightly adherent. On section, pale, rather firm. Slight fibrosis. Brain.—Superficial congestion. Base, normal. On section, normal. Intestines.—Two portions, about one foot each in length of ileum, are congested. No ulceration anywhere. Bladder.—Healthy. Contains a small quantity of urine. Urethra.—N ormal. Taking all the facts of the case into consideration, I came to the conclusion that there was a causal connection between the wound on the little finger, and the subsequent eruption and fatal termination. It was to confirm and support my hypothesis that I determined to look up the literature of Pemphigus. I have been able to collect five very c 2