Blood immunity and blood relationship : a demonstration of certain blood relationships amongst animals by means of the precipitin test for blood / by George H.F. Nuttall ; including original researches by G.S. Graham-Smith and T.S.P. Strangeways.

  • Nuttall, George Henry Falkiner, 1862-1937.
Date:
1904
Catalogue details

Licence: In copyright

Credit: Blood immunity and blood relationship : a demonstration of certain blood relationships amongst animals by means of the precipitin test for blood / by George H.F. Nuttall ; including original researches by G.S. Graham-Smith and T.S.P. Strangeways. Source: Wellcome Collection.

Provider: This material has been provided by The University of Glasgow Library. The original may be consulted at The University of Glasgow Library.

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    case where they contained egg-white. The use of such antisera is there- fore suggested where it is desired to prove the presence of egg-white in prepared foods. von Rigler (1902) treated rabbits with honey, in the manner em- ployed when they are immunified with blood. The anti-honey serum only produced precipitation in dilutions of honey, not in those of grape- or cane-sugar. Normal rabbit serum had no such effect. 5. Antiser-a in the Study of Urine. In the part referring to precipitins and precipitable substances in corpore, I referred to observations on the urine (see p. 133), which I shall not recapitulate. It is obvious that the precipitins may be put to use in the study of assimilation. I would state here that M. Ascoli (11. III. '02) succeeded by means of antiserum for egg-white, in demonstrating the existence of apparently unaltered egg-white in the urine of persons showing albuminuria in consequence of excessive al- buminous diet. Linossier and Lemoine (18. iv. '02) made observations on a young man suffering from orthostatic albuminuria, evidently due to malassimilation, the albumen being derived from non-assimilated food. On giving him cow's milk, traces thereof were found in his urine by means of lactoserum for cow's milk. Conclusions. In view of the mass of material treated of in this book, it is difficult to draw any detailed conclusions. It has been shown that there are many points of resemblance between the different antibodies. The little work which has been done with the haemolysins bears directly upon the immediate subject of this book, namely, the blood-relationship amongst animals, but it is scarcely to be expected, owing to technical difficulties, that the haemolysins will be of such general use in the study of the problem. With regard to the precipitins, it is evident that more scientific methods of treating animals for the production of antisera are called for. Powerful antisera may, however, be produced by intravenous injections of much smaller quantities of serum than have hitherto been used. Care should be exercised with regard to the addition of preservatives to anti- sera, and in the use of solvents other than salt solution for the extraction of dried bloods.