Antibiotics and antibiotic resistance / edited by Lynn L. Silver, Karen Bush.

"Resistance to antibiotics is a growing problem. This book examines the variety of different way antibiotics kill bacteria and the mechanisms bacteria develop that allow them to become resistant. Highlights include: - The Prehistory of Antibiotic Resistance - Bacterial Protein Synthesis as a Target for Antibiotic Inhibition - Tetracycline Antibiotics and Resistance - Antibacterials Developed to Target a Single Organism "-- Provided by publisher.

"Resistance to antibiotics is a growing problem. This book examines the variety of different ways antibiotics kill bacteria and the mechanisms bacteria develop that allow them to become resistant"-- Provided by publisher.

Cold Spring Harbor, New York : Cold Spring Harbor Laboratory Press, 2016.

xi, 404 pages : colour illustrations ; 26 cm.

880-01 Machine generated contents note: -- (preliminary) -- Preface -- 1. The Whys and Wherefores of Antibiotic Resistance -- C.R. Strachan and Julien Davies -- 2. The Prehistory of Antibiotic Resistance -- Julie Perry, Nicholas Waglechner, and Gerard Wright -- 5. ss-Lactam Resistance Mechanisms: Gram-Positive Bacteria -- Jed F. Fisher and Shahriar Mobashery -- 12. Polymyxin: Alternative Mechanisms of Action and Resistance -- Michael J. Trimble, Patrik Mlynárcik, Milan Kolár, and Robert E.W. Hancock -- 13. Resistance Mechanisms and the Future of the Bacterial Enoyl-Acyl Carrier Protein Reductase (Fabl) Antibiotics -- Jiangwei Yao and Charles O. Rock -- 14. Antibacterial Drug Discover Targeting the Lipopolysaccharide Biosynthetic Enzyme LpxC -- Alice L. Erwin -- 15. Topoisomerase Inhibitors: Fluoroquinolone Mechanisms of Action and Resistance -- David C. Hooper and George A. Jacoby -- 19. Bacterial Protein Synthesis as a Target for Antibiotic Inhibition -- Stefan Arenz and Daniel N. Wilson -- 20. Aminoglycosides: An Overview -- Kevin M. Krause, Alisa W. Serio, Timothy R. Kane, and Lynn E. Connolly -- 21. Tetracycline Antibiotics and Resistance -- Trudy H. Grossman -- 23. Lincosamides, Streptogramins, Phenicols, and Pleuromutilins: Mode of Action and Mechanisms of Resistance -- Stefan Schwarz, Jianzhong Shen, Kristina Kadlec, Yang Wang, Geovana Brenner Michael, Andrea T. Fessler, and Birte Vester -- 26. Antibacterials Developed to Target a Single Organism: Mechanisms and Frequencies of Reduced Susceptibility to the Novel Anti-Clostridium difficile Compound Fidaxomicin and LFF571 -- Jennifer A. Leeds -- 27. Fusidic Acid -- A Bacterial Elongation Factor Inhibitor for the Oral Treatment of Acute and Chronic Staphylococcal Infections -- Prabhavathi Fernandes -- Index.

Includes bibliographical references and index.