Studies from the research laboratory of the Connecticut Agricultural Experiment Station : the nucleic acid of the wheat embryo / by Thomas B. Osborne and Isaac F. Harris.

  • Osborne, Thomas B. (Thomas Burr), 1859-1929.
Date:
[1902]
Catalogue details

Licence: In copyright

Credit: Studies from the research laboratory of the Connecticut Agricultural Experiment Station : the nucleic acid of the wheat embryo / by Thomas B. Osborne and Isaac F. Harris. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    3. That there are phosphorus- and protein-containing sub- stances of similar solubilities which, however, do not contain the true nucleic acid, but other acids from which the charac- teristic decomposition products of nucleic acid cannot be obtained. These latter acids are now known as para- or pseudo- nucleic acids. 4. That the true nucleic acids are strong polybasic acids, con- taining the purin, pyrimidin and carbohydrate groups and yield on hydrolysis orthophosphoric acid. 5. That there is at least one other acid which contains the purin and carbohydrate group and also yields orthophosphoric acid, but is a substance of a different order since it contains glycerine and lacks the pyrimidin group. 6. That there are at least two true nucleic acids—one con- taining thy min, the other uracyl. 7. That the ultimate composition of these acids is not yet settled, though the more carefully purified preparations have a similar composition. The results of the analyses of different nucleic acids have led to the following formulas: Salmon Milt. C44H64N12P4O32 Miescher.* C40ft54bl 14P4O27 Miescher and Schmiedeberg. C40H56N14P4O26 Schmiedeberg. C40H50N14P4O26 Herlant. Thymus of Calf. C40H00N10P4O25 Kossel.* C40H6oN]4P4O28 Herlant. Arbacia. C40hi54hi14P4O27 Mathews. Pancreas. C42H04N 10P 1 C43H73N17P4 Spleen. C42H74N17P4 ► Levene.f Codfish Milt. C40H70N17P4 Calculated to a basis of four P atoms, f Ratio calculated by the writer from Levene’s analyses.