BetaThis search tool is in development. Find out more.
Digital Images

HMG-CoA reductase

T. Greenhough & A. Shrive

Available online

view HMG-CoA reductase


Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

You can use this work for any purpose, as long as it is not primarily intended for or directed to commercial advantage or monetary compensation. You should also provide attribution to the original work, source and licence.

Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) terms and conditions

About this work


Molecular model of human enzyme HMG-CoA reductase. This enzyme catalyses the first step in the cholesterol biosynthesis pathway and is inhibited by statins. The four protein subunits are shown in blue, turquoise, yellow and red. Pink highlights the CoA and green, the molecule that will be released from the enzyme as mevalonate.


We’re improving the information on this page. Find out more.