Observations on box (buxus sempervirens), with especial reference to the true nature of tetanus / by Sydney Ringer and William Murrell.

  • Ringer, Sydney, 1835-1910.
Date:
1876
Catalogue details

Licence: Public Domain Mark

Credit: Observations on box (buxus sempervirens), with especial reference to the true nature of tetanus / by Sydney Ringer and William Murrell. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    tlie unprotected would progress more rapidly than in the protected leg. Again, if box affects either the nerves or muscles before the spinal cord, then loss of reflex action should occur earlier in the unprotected than in the protected limb. Now, we find as the result of seven observations given in the subjoined table, in which one iliac artery was tied, that with only one readily explicable exception, tetanus was equally well marked, that paralysis progressed equally, and was complete at the same time in both legs; moreover, the loss of reflex action begun simultaneously in both legs. Table showing comparative amount of tetanus and paralysis in the legs produced by box after ligature of the iliac arteries. Experiment Date. Weight of frog. Dose of extract. Proportion of dose to weight of frog. Vessels tied. Result. 1876. Grms. Grains. XXXIV April 25 76 30 Lt. iliac Tetanus less in left leg than in right XXXV „ 25 65 27 Kt. iliac Tetanus slightly less in left leg than in right XXXVI „ 26 25 9 ff Tetanus equal LV May 2 24 12 ff Tetanus equal; loss of reflex action equal LVI „ 2 25 12 ••• if Tetanus equal; reflex action slightly greater in right leg LVII „ 2 22 12 ff Tetanus equal; reflex action slightly greater in right leg before in- jection; subsequently no difference could be detected LVIII » 2 19 9 if Tetanus equal; reflex action equal in both legs Average 38 14 ...