The healing of arteries after ligature in man and animals / by J. Collins Warren.

  • Warren, John Collins, 1842-1927.
Date:
1886
Catalogue details

Licence: Public Domain Mark

Credit: The healing of arteries after ligature in man and animals / by J. Collins Warren. Source: Wellcome Collection.

Provider: This material has been provided by the Augustus C. Long Health Sciences Library at Columbia University and Columbia University Libraries/Information Services, through the Medical Heritage Library. The original may be consulted at the the Augustus C. Long Health Sciences Library at Columbia University and Columbia University.

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    of the media, and are entangled in fibrine-fibres. These together form quite a mass, filling the central third of the thrombus for some distance. The thrombus is irregularly laminated, and has, when seen with a low power, a marbled appearance, the irregular arrange- ment of the fibrine and white corpuscles, which are always together, breaking the mass of red corpuscles up into lobules of varying size. The clot is exceedingly tough and difficult to cut with the micro- tome, owing apparently to its density. It terminates in a short pyra- midal apex consisting of fibrine and white corpuscles. The walls of the vessel throughout, except at this terminal point, are adherent to it, and, as the thrombus diminishes considerably in ''-cumference in its lower half, are much contracted at this point.presear the apex there is a marked thickening of the intima, show:e momder a high power, a growth of spindle and round cells, whictthe ccect into the clot a short distance, and, when broken away fum of /present a serrated edge. Nowhere else is any such char prepared w intima found. There is little change seen in the walls ofting the moortion. A small fragment of clot, composed of red corpusrtological elt still to the ruptured surface. There is not the same;g to determ'face as upon the proximal side of the ligature, but the \ the preparats to be thrown into a series of folds radiating from thpine and theThe ap- pearances of both sides of the ligature closely \ both in Can22 shown in Fig. 2. Following the walls of the vessf a slight thickening of the intima is observed at tig the period of the vessel on the sides opposite the angle, a po^-e had been drtion of this thrombus ends. .-d appear direct Remarks.—In this specimen all externaljow cylinder, corlissected away in accordance with the usual method^s slightly separat It is an interesting fact that no signs of new tissue-ow cord. Both be found within the vessel, except at a point quite remote-iru-Ai-,,.,, ligature. The growth in the intima near the apex of the thrombus both favors •the narrowing of the lumen, and serves to hold the thrombus firmly in place. Is such a growth to be regarded as of traumatic origin, or simply as a formative process intended to adapt the parts to new conditions ? There is evidently a true dilatation of the proximal end of the vessel, for the walls are put upon the stretch, and much thinned; the appearance is not produced by the contraction of the vessel below. The appearance of the distal portion of the vessel at the point of Ugature is the one usually seen. The fact that the ruptured edges