The relation of the mono-molecular reaction to life-processes and to immunity / by John Brownlee.

  • Brownlee, John, 1868-1927.
Date:
1911
Catalogue details

Licence: In copyright

Credit: The relation of the mono-molecular reaction to life-processes and to immunity / by John Brownlee. Source: Wellcome Collection.

Provider: This material has been provided by The University of Glasgow Library. The original may be consulted at The University of Glasgow Library.

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    TABLE IV. Table showing the Case Mortality for Small-pox among the Vaccinated, Gloucester, 1895-6. Age Period. Cases. Deaths. Case Mortality. Actual. Theor. 20-30 367 23 6'2 8-1* 30-40 272 29 106 10-6 40-50 142 21 14-8 13-8 50-60 63 12 19-8 18-0 (.0-70 34 8 23-5 23-6 70-80 13 4 30-8 30-8 * Age when the law does not hold. For all ages x2 = 2'4 P = '62. For ages above 30 ^ P = '91. With regard to small-pox, Table IV., the' Gloucester figures show a very good agreement between fact and theory. From 30 upwards the concord- ance is exact. The theoretical figures were fitted to the mortality rates for the latter years, and that for the age period 20-30 thence calculated. When the whole series thus obtained is considered, the value of P is not specially high, but for the period above 30 years the fit is exceptionally good. 3. Gompertz’ Law.—This law is the product of an earlier science, and has almost been forgotten. Briefly expressed, it is to the effect that the liability to death increases in a geometrical progression with age. Its truth is undoubted for all ages above 50 for both sexes. In this law Makehain made a change which rendered it much more convenient to actuaries, but which obscured the biological significance of the original statement. The following figures from the Registrar-General’s tables for England sufficiently explain the facts:— TABLE V. Showing the Average Death-rate in Males and Females at Ages 55 and Upwards for the Period 1858-1901. Age Period. Males. Females. 55-65 333 28 1 65-75 68-3 60-0 75-85 147-4 133-3 85- 308 6 281-9 The death-rate thus approximately doubles itself every ten years.