On the detection of aconite by its physiological action : being notes of experiments made in connection with the trial of Dr. E. W. Pritchard / by Frederick Penny and James Adams.

  • Penny, Frederick, 1816-1869.
Date:
1865
Catalogue details

Licence: Public Domain Mark

Credit: On the detection of aconite by its physiological action : being notes of experiments made in connection with the trial of Dr. E. W. Pritchard / by Frederick Penny and James Adams. Source: Wellcome Collection.

Provider: This material has been provided by The University of Glasgow Library. The original may be consulted at The University of Glasgow Library.

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    four to eighteen of the hitter. In one instance death was caused by one grain mixed with nine; in another, two grains mixed with ten. In both instances the poison was injected beneath the skin. There was caused by a mixture of these agents an evident blendino of the symptoms produced by both, but the action of the aconite predominated. When, however, the Battley was employed in the Large proportion of eigliteen to one of the aconite, the conditions were reversed. When a full dose of both in a state of mixture was used, there was at first less of the active uneasiness than was noticed with the aconite alone, on the con- trary, a stronger disposition to couch or rest was manifested; but when doing so, the head was invariably carried erect. On being urged to motion, the hobbling or crawling progression, as opposed to the spasmodic jerking action observed with aconite, was more strono-ly marked. The convulsive seizures did not, however, seemto be lessened in severity, but the intervals of relaxation were longer, and during these intervals the action of the J3attley became evident. pritci-iaed's battley. The symptoms are so closely similar to those of Battley's solution mixed with aconite, that, nomine mutando, the one will pass for the other. No possible distinction could be dm^n from the appearances presented by an animal suffering from the effects of a dose of Pritchard's Battley and of another undergoing, at same time, the effects of a mixture of Battley and acomte. We thiik it preferable to indicate thus shortly the action of Pritchard's Battley, instead of summarizing its effects, as we have done with aconite and Battley's solution,respectively, because m all experiments wherein vital action is exhibited, there will ^ISly be found some points of difference ^^^^^ order or character of individual phenomena. . trnf^.^^^^* descHption we have given of the effects of aconite and ol Battley s soTu on when used alone, is sufficiently clear for the pui^ose of view we believe that the larger number and fuller detai s ^e Im e I vInTn the Appendix, of experiments with Pntchard s Bat ley S enrbirour readers'bette^^ appreciate the nature of those joints of sM which we oui.elves were satisfied regardmg the composition of Pn^^^^^^^^^ No. 27 and No. 34, it