Atlas and epitome of human histology and microscopic anatomy / by Johannes Sobotta ; edited, with extensive additions, by G. Carl Huber.

  • Sobotta Johannes, 1869-1945.
Date:
1903
Catalogue details

Licence: In copyright

Credit: Atlas and epitome of human histology and microscopic anatomy / by Johannes Sobotta ; edited, with extensive additions, by G. Carl Huber. Source: Wellcome Collection.

Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.

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    Plate i.—mitosis. Figs. 1-10.—Ten Stages of Indirect Nuclear Division (Mito= sis) from the Oral Epithelium of the Larva of a Salamander. X -'■jOO. Tccliilic : Chroiiiio acid solution, 2 per cent. Hematoxylin and eosiii. Fig. 1.—Cell with resting nucleus a short time before the begin- ning of the mitosis. The nucleus shows distinct, irregularly con- toured threads. Fig. 2.—The nucleus of the cell is at the hcginning of mitosis. Distinct chromatin loops (chromosomes) are recognized. Stage of the close, .skein. Fig. 3.—The nuclear membrane has disii])peared. In place of the nucleus lie,s a loo.se .skeiu of chromo.somes (the pole held is at the left). I’ig. 4.—Mother star (monaster) viewed from above. Fig. ,^).—Mother star (mona.ster) viewed from the side. The ehro- mosome.s, except two, are groui)cd around the equator of the achro- matic s])iiKlle. Fig. ().—.Mother star viewed from the side. The chromo.somes ci'owded closely around the e(iuator of the spindle. h'ig. 7.—Stage of mehikinesis. One-half of the longitudinally divided chromo.somes is drawn toward each ])olc of the spindle. h'ig. H.—Hcginning constriction of the cell-body. Stage of the daugbter star (<liaster). Fig. !).—(’om])letion of cell division. Transformation of the daughter stars into sk(‘ins (di.s])irem). Fig. 10.—Change, of skeins into resting daughter nuclei (complete daughter celts, telophase). Keference lettei-s : e, Centro.some; ch, chi'omosomes; ^9, polar rays; .s/9, achromatic spindle ; x, scattered chromosomes. tlic arrangeiiiont of the chromo.somes is .still more distinct. These are now very regularly arranged and next undergo a h)if/ilu(Unal cleat'age of such a kind that each chromo- some is divided longitudinally into two daughter chromo- .some.s, which, however, .for a variable time rcmtiin in close apposition, and for this reason this longitndinal division is not observed iit this time nidess the magnitiea- ti(9ii is snffieientlv high. At the .same tinu', the nnelear membrane disappears and the nnelear (Inid mingles with the c(‘ll protoplasm; the cell has no longc'r a eirenmserihed nucleus. The cc'utro.somc, in case the resting (X'll did not (contain two, now divides into two halves, whieh move apai’t, and a small achromatic spindle can now he reeog-