Relaxed skeletal muscle showing sarcomeres & nucleus

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Relaxed skeletal muscle showing sarcomeres & nucleus. University of Edinburgh. Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). Source: Wellcome Collection.

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Transmission electron micrograph of myofibrils within an uncontracted skeletal muscle fibre (a single muscle cell) of a guinea pig. One of the cell's nuclei is also visible. Each myofibril is made up of sarcomeres (contractile units) A sarcomere extends from one heavy black line (Z line) to the next. The actin filaments extend from the Z line towards the centre of the sarcomere. The myosin filaments form the dark band in the centre of the sarcomere. These 2 types of filaments slide over each other to cause the muscle to contract.

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