Mutation as cellular process : a Ciba Foundation symposium / edited by G.E.W. Wolstenholme and Maeve O'Connor.

  • Symposium on Mutation as Cellular Process (1969 : London, England)
Date:
1969
Catalogue details

Licence: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

Credit: Mutation as cellular process : a Ciba Foundation symposium / edited by G.E.W. Wolstenholme and Maeve O'Connor. Source: Wellcome Collection.

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    242 INDEX OF SUBJECTS Mutagenesis, u.v. induced {continued) pnenotypic characteristics, 207, 208 repair, 88 et seq., 139 visible light induced, 174-178 X-ray induced, 178-179, 183-184 Mutants, assay of frequency, 88-89, 103 latent T5-resistant expression, 99-100, lOI frequency, 88-89,103 growth rates, 95, 96, 97, 103,104 photoreactivation, 99 rate of disappearance, 93-94 repair of, 87-106 selection against, 90-93 temperature dependence, 94 yield, 95-96, 97, 106 repair gene, 18 repairless, 18 Mfd mutants, 21, 26, 28 Mutation(s), at low incubation temperatures, 205 frequency in mice, 216-228 in phage x, u.V. induced, 3-6, 13 X-ray induced, 4, 6,14,16 kinetics, 95 photoreversibility of, 204 rates, 103 reverse, 211 spontaneous frequency, 206 to virulence in £icAenc/ii<j coli, 107 c-Mutations, 3 et seq. Mutational pathways, 17 Mutational synergism, 36 Mutation frequency decline, 19-26 effect of tryptophan, 20, 32 for forward mutation, 31 inhibition, by amino acid pool, 19, 20 nature of, 25-26, 31, 32-34 role of incubation, 28-29 survival recovery, 24, 34 Nalidixic acid, 212 Neomycin resistance, 155, 156, 157, 159, 160, 169 Neurospora, mutagenesis in, 51 mutation rates, 197 mutation specificity in, 66-86 photorepair, 57 u.V. mutagenesis, 51 et seq. Neutron irradiation, 225, 226, 227 repair and, 226 Nitrosomethylurethane, mutagenesis in¬ duced by, 66, 68, 84 Nitrosoguanidine, 26 Nitrous acid, mutagenesis by, 66, 70 Nonsense suppression, 158, 161 in yeast, 196 Nuclei, number in cell, 102 Nucleic acids, alkylation of, 138-154 modification in mutational processes, 171-185 sensitivity to X-rays and thermal neutrons, 179 u.V. irradiation, 109-137 Nucleotides, role in mutation production, 133 One-hit mutational events, 13, 218, 226 Oocytes, repair in, 220, 222, 227 Ophiostoma, 61 Paramecium, 214 Penicillinase, 211 Peroxide, protective effect, 175 Phenotypic expression, effect of caffeine, 44 Photoreactivation, 170 in repair, 99, 203 of thymine, 177 of u.V. inactivated polyuridylic acid, 175 Photorepair, 57-58, 60, 63 of inositol allele, 76 PhotoreversibiHty of mutations, 204 Pleiotropy, of ribosome mutations, 155- 156, 158 Polyadenylic acid, reiteration of, 121 Polyamines, 26 Polycytidylic acid, action of u.V., 173 modification of, 112-115 Poly guanyladeny late, 114 Polynucleotides, effect of MNNG on coding properties, 180 Polyribocytidylic acid, half-life, 131 Polyribonucleotides, as templates, 112 Polyuridylic acid, photohydration, 134 reiteration, 121 u.V. inactivated, photoreactivation, 175