Licence: In copyright
Credit: Vincent's angina / by J.D. Rolleston. Source: Wellcome Collection.
Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.
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![present in five successive cultures, but smears showed numerous fusiform bacilli and spirilla. In spite of applications of iodine twice daily, the ulceration persisted until July tho 7th, when she was given a mi.xturc containing liq. hydrarg. pcrchlor. and j^ot. iod. thrice daily. Within a week the ulcers had completely healed. Apart from the therapeutic result, there was nothing to suggest syphilis in this case beyond some flattening of the bridge of the nose. The value of Wassermann’s reaction, which at that time had not been discovered, is obvious in a case of this kind, as Sobernheim has recently shown in dealing with the co-existence of Vincent’s angina and latent acquired syphilis. No other instances of the co-existence of Vincent’s angina and inherited syphilis have been recorded, but there have been several cases published of ^’^incent’s angina in all stages of the acquired disease. In Lagriffoul and Bousquet’s case typical Vincent’s angina shortly preceded the roseola. In tho cases of Malherbe, Moutot, and Salomon, symptoms of secondary lues were already present. In Sobernheim’s case the Spirochwta pallida was associated with Vincent’s organisms in the throat lesions. Sack records a case of the co-existence of Vincent’s angina with tertiary syphilis, in which recovery took place under iodide of j)otassium. It is interesting to note in this connection as illustrative of the action of the fuso-spirillar couple in ulcers situated elsewhere than in the bucco-pharyngeal cavity, that Launois and Laederich found Vincent’s organisms in a phagedajnic chancre of the penis, together witli the Spirochn’ta pallida. An instructive case is recorded by Balzer and Poisot of the association of Vincent’s organisms with Ducrcy’s bacillus in gan- grenous soft chancre. As in Vincent’s angina, the general condition did not correspond to the local lesion. The temperature was normal and the pulse 76. That the local malignancy was due rather to Vincent’s organisms than to the organism of soft chancre was ])roved by the considerable improvement which followed the applica- tion of methylene-blue. The fuso-spirillar coiqdo completely disappeared in two days, though Ducrey’s bacillus still jiersisted. Hebert’s unique case may also be mentioned here. A man suffering from specific urethritis developed stomatitis of tho gums and cheeks, associated with angina, bacteriological e.xamination of which showed gonococci and Vincent’s organisms. Tlie case was successfully treated with a gargle and mouth-wash of potassium permanganate.](https://iiif.wellcomecollection.org/image/b22433491_0012.jp2/full/800%2C/0/default.jpg)
