Epilepsy, comparative pathogenesis, symptoms, treatment / [Louis Jacob Josef Muskens].

  • Muskens, L. J. J. (Louis Jacob Josef), 1872-1937.
Date:
1928
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Licence: In copyright

Credit: Epilepsy, comparative pathogenesis, symptoms, treatment / [Louis Jacob Josef Muskens]. Source: Wellcome Collection.

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    increase (Cliaslin, Bleuler, Alzheimer, Jakob). It would also appear that changes in the cornu ammonis occur more frequently here than in other psychoses. We know as a result of operations that quite frequently in focal epilepsy nothing is found except a milky appearance of the pia mater (Tillmann, Kramer, Volland, Muskens). With the exception of one case by Claus and Van der Stricht, we have no information about the changes in incipient or arrested epilepsy. It is not a matter for wonder, therefore, that Marinesco and Bouche called the results of anatomical investigation “negative.” Burlureaux styled them as extensive as they were unimportant. It is a fact that many authors agree with Binswanger, and do not consider as proved that genuine epilepsy is due to an organic alteration. Huntington’s chorea is looked on by many as being related to myoclonic epilepsy. Anatomical examination has here again Fig. 44.—On the Left Side Normal Ammon's Horn; on the Right Side the Convolutions are Atrophic. given very little result. Facklam, Keraval, and Raviart found changes in the Rolandic convolutions (Rossi and Gonzalez found similar changes in myoclonia). Jelgersma and Vogt found changes in the corpus striatum, while Gezelle Meerburg also found, in addition, changes in the cortical ganglionic cells. Attention must be called to the discrepancy between the great importance assigned by neurologists to encephalitic cicatrices and the rarity with which such lesions are described anatomically. This is evident from the foregoing review, and it is also apparent in the Annual Reports o'f Autopsies in the Craig Colony, especially those given by J. F. Munson. A case of epilepsy is, however, reported by Mingazzini,* where there was a lesion (?) in the Rolandic convolutions, and Ivogerer reports a cicatricial lesion in a case of lepto-meningitis.f This discrepancy may be due to encephalitic lesions incurred * Mingazzini, Beitr. zuv pathol. Anat. u. Psych., 1920, vol. lix. f Kogerer, Zeitschr.f. d. ges. Neurol, u. Psych., vol. xix., 1920.