A manual of pharmacodynamics / by Richard Hughes.

  • Hughes, Richard, 1836-1902.
Date:
1886
Catalogue details

Licence: Public Domain Mark

Credit: A manual of pharmacodynamics / by Richard Hughes. Source: Wellcome Collection.

Provider: This material has been provided by the Francis A. Countway Library of Medicine, through the Medical Heritage Library. The original may be consulted at the Francis A. Countway Library of Medicine, Harvard Medical School.

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    the bronchial tubes must be put out of court altogether, as not warranted by the facts ; but simple bronchitis and pneu- monia (lobar) have not infrequently been observed in human poisoning. The same may be said of albuminous nephritis ; but not of the hepatic and ocular symptoms specified, or of the convulsions. Of Fluoric acid the symptoms I have cited as noteworthy must be read in their connexions, as you will find them in the Cyclopcsdia. In this light several of them look very differently from their appearance in the schema; and some will not be found at all, as being unconfirmed results of dilutions higher than the 6th. Of fresh therapeutic applications I have a curious one to mention. In the Lancet for 1881 (i., 497), Dr. Woakes relates twenty cases of goitre treated by him with the acid, of which seventeen were cured. He explains his use of it by pointing to the analogy of fluorine with iodine and bromine, both of which have proved anti-goitrous remedies ; so that he was induced to try this their near relative. It may have been so; but one cannot help sus- pecting that he had come across the facts I have related, of the production of bronchocele in a dog by fluoride of potas- sium in the hands of M. Maumen^ and his ascription of the disease generally to the presence of fluorides in the drinking water. Anyhow, it is a pretty piece of homoeopathic practice, and deserves imitation. Dr. Woakes gave 5ss—3ij doses of a \ per cent, solution. Of Nitric acid I would say that you will find Scott's and Wunderlich's cases in full in the Cyclopcedia, with some additional observations of its pathogenetic effects. In speaking of Phosphoric acid as having more than once proved curative of purpura and passive haemorrhages, I should have used the more than once of the latter only. I know of but one case of purpura reported as cured by it, viz., that in Frank's Magazin, ii., 581; but there are cases of metrorrhagia and haemoptysis in which it was the remedy in this and other parts of the same collection (ii., 581 ; iv., 737), and testimonies to its value in such affections are adduced by Marcy and Peters. About Aconite I have several points to make. i. As regards the preparation, the new edition of the Pharmacopeia directs that the ordinary tincture (to be dispensed unless the other is specified) shall be made from the freshly collected leaves and flowering tops only. The tincture of the root (fresh or dry) is to be made with proof spirit by percolation. 2. I am bound to say that the rendering of Schroff's experi-