The relation between amylase retention and excretion and non-protein nitrogen retention in experimental uranium nephritis / R. Fitz, M.D. Boston.

  • Fitz, Reginald, 1885-1953
Date:
1915
Catalogue details

Licence: In copyright

Credit: The relation between amylase retention and excretion and non-protein nitrogen retention in experimental uranium nephritis / R. Fitz, M.D. Boston. Source: Wellcome Collection.

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    Third day. (Wt. 1,900 gm.) Urine: twenty-four-hour amount . 100 c.c. “d” ...;. 32 absolute diastatic strength . 1,600 Fourth day. (Wt. 1,900 gm.) Urine: twenty-four-hour amount. 75 c.c. “d” . 32 absolute diastatic strength. 1,200 Fifth day. (Wt. 1,850 gm.) Urine: twenty-four-hour amount . 80 c.c. “d” . 32 absolute diastatic strength . 1,280 Sixth day. (Wt. 1,850 gm.) Urine: twenty-four-hour amount. 110 c.c. “d” . 16 absolute diastatic strength . 880 Blood: serum “d” . 64 non-protein nitrogen (per 100 gm.). 78 mg. Histological Findings: Glomeruli negative; considerable necrosis and des¬ quamation of the epithelium of many tubules; a few tubules filled with necrotic material; many tubules lined with regenerating epithelium. Experiment 6.—Rabbit killed on the sixth day after the administration of the uranium nitrate. First day. (Wt. 2,100 gm.) Urine: twenty-four-hour amount. 80 c.c. “d” . 16 absolute diastatic strength . 640 Blood: serum “d” . 64 non-protein nitrogen (per 100 gm.). 35 mg. Administered 7 mg. uranium nitrate. Second day. (Wt. 2,100 gm.) Urine: twenty-four-hour amount . 65 c.c. “d” . 64 absolute diastatic strength. 2,080 Third day. (Wt. 2,100 gm.) Urine: twenty-four-hour amount . 100 c.c. “d” . 64 absolute diastatic strength. 3,200 Fourth day. (Wt. 2,000 gm.) Urine : twenty-four-hour amount . 60 c.c. “d” . 64 absolute diastatic strength. 1,920 Fifth day. (Wt. 2,000 gm.) Urine: twenty-four-hour amount . 10 c.c. “d” . 4 absolute diastatic strength. 20 Sixth day. (Wt. 2,000 gm.) Urine: twenty-four-hour amount . 20 c.c. “d” . 8 absolute diastatic strength . 80 Seventh day. (Wt. 2,000 gm.) Urine: twenty-four-hour amount . 30 c.c. “d” . 4 absolute diastatic strength. 60 Blood: serum “d” . 128 non-protein nitrogen (per 100 gm.). 217 mg. Histological findings: Hyaline droplets in many glomeruli; considerable necrosis and desquamation of the epithelium of many tubules; many tubules filled with necrotic material and casts; many tubules lined with regenerating epithelium.
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