Elements of pharmacy, materia medica, and therapeutics / by William Whitla.

  • Whitla William, Sir, 1851-1933.
Date:
1898
Catalogue details

Licence: Public Domain Mark

Credit: Elements of pharmacy, materia medica, and therapeutics / by William Whitla. Source: Wellcome Collection.

Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.

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    dangerous remedy, and should not be given in dose* of more than 5 to 10 minims liquid extract (i in i). The powdered root has been applied to burns and eczema (i to 8 lard). The powdered extractive known as Phytolaccin has l>een used as a cholapopue in liver diseases in doses of 2 to 3 pTs. Pichi, or Fabiana imbrioata, ha- been tried in a number of diseases since Rusby and Ramircs have reported upon it. It consists of the younp branches, which they have found to be powerfully diuretic and tonic. Its use is contra-indicated in advanced renal diseases. In chronic catarrh of the bladder and in cystitis, accompanied by calculi and gravel, this drup has been much prized in Chili, and Fenwick found it to pos-e-s consider- able power over the ha-maturia and pain in renal calculus. Shoemaker states that, given in combination with an alkali.it holds uric acid in solution, and it is thought that its resin dissolves the mucus which bind.- together the panicles of a stone, leading to disintegration and facilitating expulsion. It has been given in nocturnal enuresis. Dose of fluid extract (l in I), J to I dr. ; in infusion (l in 20), 2 ozs. Piper Methysticum. (Sec Kava Kava.) Piperazine 1- a U >dy in curring in colourle- . a< i< tilar 1 ry-ub, very soluble in water, prepared synthetically from ethylenedia- inine, and is known as Fthylenimine, Diethylendiamine or Dispermine. Its formula is C4Il10Na. It was at first introduced under the name Spermine, having been considered to be identical with that Kxly, but it has nothing in common with it. It behaves in a remarkable manner with uric acid. In cold aqueous solution it dissolves heehe times as much uric acid as carbonate of lithium does under identical conditions, and the piperazine-uric acid compound is seven times more soluble than the lithium-uric arid combination. It is claimed that 1 |»art of piperazine and 1 part of uric arid dissolve in less than I drachm of water, whilst it requires nearly 1 ounce of water to dissolve the same quantity of uric acid lithium (the exact proportions being 50 and 368 parts). Even when the uric acid is in great excess piperazine forms the very soluble neutral salt, and never an acid salt. An injection into the bladder has been recommended as a solvent of uric acid calculi. It is non-caustic and harmless, and may be given hypoder- mically in doses of 5 grs., or by the mouth 6 grs., three limes a day in a large quantity of plain or aerated water. According to the reports of many observer- it has proved a valuable solvent for uric acid calculi. Vogt found that 15 grs. three times a day markedly increased the amount of urea and diminished the amount of uric- acid in the urine ; it also increases the quantity of urine passed