Detecting cancer in human tissues, LM

  • Aamir Ahmed, Jane Pendjiky and Michael Millar
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Detecting cancer in human tissues, LM. Aamir Ahmed, Jane Pendjiky and Michael Millar. Attribution 4.0 International (CC BY 4.0). Source: Wellcome Collection.

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Fluorescence immunohistochemistry and confocal microscopy were used to image this array of normal and cancerous human tissue samples (32 in total). Human prostate, colon, kidney, intestine and breast tissue sections were stained for the presence of protein biomarkers (QuiPCaMs), which are being researched in order to improve cancer diagnosis and prognosis. The presence of three different proteins, all biomarkers of cancer, was simultaneously detected using a different fluorescent marker (green, blue, red) for each. Each circle (whole tissue core) is 0.6 mm in diameter.

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