BetaThis search tool is in development. Find out more.
Digital Images

Aniridia + deletion, FISH probes

Wessex Reg. Genetics Centre

Available online

view Aniridia + deletion, FISH probes

License

Attribution 4.0 International (CC BY 4.0)
You can use this work for any purpose, including commercial uses, without restriction under copyright law. You should also provide attribution to the original work, source and licence.
Creative Commons Attribution (CC BY 4.0) terms and conditions https://creativecommons.org/licenses/by/4.0
Credit: Aniridia + deletion, FISH probes. Credit: Wessex Reg. Genetics Centre. Attribution 4.0 International (CC BY 4.0)

Selected images from this work


About this work

Description

Human chromosomes highlighted by fluorescent probes which bind to specific sequences of DNA. This FISH (fluorescence in situ hybridisation) study is of a patient with aniridia and a cytogenetically visible deletion in chromosome 11, 11p13p15.1. The chromosome 11 centromeres are shown in green. The upper cell shows that the deletion includes the aniridia gene (PAX6) (red) but does not include the Wilm's tumour predisposition gene WT1 (shown red in lower cell). This result suggests that this patient is at low risk for developing Wilm's tumour. Image by Dr John Crolla.


Permanent link


We’re improving the information on this page. Find out more.