Leg of a woman with an advanced ichthyotic condition of the skin

Watercolour drawing of the right leg of an unmarried woman, aged 21 years, who had an advanced ichthyotic condition of the skin of the thigh and leg. The skin of the thigh has a remarkably papillated appearance. The papillae appear to be due to hypertrophy of the epidermis, for they could be readily picked off, leaving the Malphigian layer exposed. At the line of flexion of the joints the skin was smooth, being devoid of papillae. The drawing shows the amount of hyper-extension present at the knee joint.