Volume 3

Gene expression / Benjamin Lewin.

  • Lewin, Benjamin.
Date:
1974-1977
Catalogue details

Licence: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

Credit: Gene expression / Benjamin Lewin. Source: Wellcome Collection.

    12/952 (page VIII)
    that is the only option for survival open to nonlysogenic phages. Obvi ously it is scarcely possible to consider in a single volume all the systems that now have been investigated and discussion therefore concerns the best characterized: the large phage T4, the smaller phages T3 and T7; the single stranded DNA phages; and the RNA phages. In this book as in the earlier volumes, I have been concerned not simply to summarize what is thought to be the status quo, but to consider critically the original experiments and to establish the limits of the conclu sions that can be drawn from them. Sometimes, of course, my conclu sions may differ from those of the authors reporting the data. And obvi ously it is as important to ask questions as to provide answers: any attempt to define the conclusions supported by current data can hardly be divorced from consideration of their further implications. I have tried therefore to point to the questions that may now be asked and to consider the lines along which their resolution may be possible. I have followed my usual policy on references; I have attempted to provide a complete citation of those papers that comprise the mainstream of research (some 2000 in this volume) but without necessarily referring to every confirmatory report. Virtually all the references cited represent papers published in the major research journals; only in those rare in stances where no other source is to be found have I relied upon contribu tions to symposia and other such volumes. Finally it is a pleasure to thank colleagues who have provided material included in this book and especially Drs. E. P. Geiduschek and W. Szybalski, who read some of the chapters and made many helpful comments. Although any expression of gratitude here can only be in adequate, I should like to conclude by thanking my wife, Ann, without whose encouragement this book would never have been started nor com pleted. Benjamin Lewin Cambridge, Massachusetts January 1977