Mouse hand plate

  • Kate Storey
  • Digital Images
  • Online

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Attribution 4.0 International (CC BY 4.0)

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Credit

Mouse hand plate. Kate Storey. Attribution 4.0 International (CC BY 4.0). Source: Wellcome Collection.

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Description

Light micrograph of a developing mouse limb showing gene expression in the hand plate. The hand plate is a flattened extension of the limb that will go on to form the hand. The hand plate has been stained using a technique called in situ hybridisation to highlight a gene involved in the development of the hand, the regions highlighted will undergo apoptosis (cell death) to form the digits. This stage of limb development occurs around 12.5 - 13.5 days post fertilization in the mouse.

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