Amyloid fibrils

  • Dr. Wei-Feng Xue
  • Digital Images
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Amyloid fibrils. Dr. Wei-Feng Xue. Attribution 4.0 International (CC BY 4.0). Source: Wellcome Collection.

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Negative stain, transmission electron micrograph of a beta2-microglobulin fibril sample that was grown in vitro under agitated conditions. Amyloid fibrils are formed through a complex assembly process that result in fibrils, from which small fragments can break off to seed new fibrils, like a dandelion clock that disperses with the wind. Amyloid assembly results in numerous human diseases, such as Alzheimer’s, Creutzfeldt-Jakob disease (CJD) and diabetes.

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