Find thousands of books, manuscripts, visual materials and unpublished archives from our collections, many of them with free online access.
Search for free, downloadable images taken from our library and museum collections, including paintings, illustrations, photos and more.
Exosomes on surface of HeLa cell
- Dr James Edgar, Cambridge Institute for Medical Research, Cambridge
- Digital Images
Attribution 4.0 International (CC BY 4.0)
You can use this work for any purpose, including commercial uses, without restriction under copyright law. You should also provide attribution to the original work, source and licence.
Creative Commons Attribution (CC BY 4.0) terms and conditions https://creativecommons.org/licenses/by/4.0
Selected images from this work
About this work
This image shows a scanning electron micrograph of the surface of a HeLa cell (pink) that has been treated with a drug to induce exosome (blue) release. Exosomes are a type of vesicle, or fluid-filled space surrounded by a membrane, that are released from cells. Our understanding of how they behave is in its infancy, but exosomes have already been implicated in numerous disease states, including neurodegenerative diseases and cancer. Here, it is shown for the first time that exosomes remain associated to the surface of cells following their expulsion from the cell. The image helps to demonstrate that exosomes are retained in small clusters, and further work has shown that these clusters are held together by the protein 'tetherin' which plays a similar role in holding viruses to the surface of cells as a means of limiting viral spread.