On hæmatoporphyrin as a urinary pigment in disease / by Archibald E. Garrod.

  • Garrod, Archibald E. (Archibald Edward), Sir, 1857-1936.
Date:
1892
Catalogue details

Licence: Public Domain Mark

Credit: On hæmatoporphyrin as a urinary pigment in disease / by Archibald E. Garrod. Source: Wellcome Collection.

Provider: This material has been provided by The University of Glasgow Library. The original may be consulted at The University of Glasgow Library.

    8/20 (page 4)
    Secondly, cases in which the acid spectrum was alone obtained, some of which would doubtless have been included in the previous group had a larger amount of the urine been available for examination. In the third group are included those cases in which no trace of haematoporphyrin could be detected in the urine. It will be noticed that the cases were not by any means taken at random, but that any promising hne of investigation was followed up, as far as the supply of material allowed, with the result that more than half the patients were suffering from one of some six or seven maladies. It is therefore probable that the proportion of cases in which htemato- porphyrin was found in notable excess is considerably greater than would have been the case if no such selection had been exercised. It seemed desirable to study not only the occurrence of haemato- porphyrin in the urine in different diseases, but also the relation of the increased excretion of the pigment to the other morbid phenomena; and accordingly many specimens of the urine were in some cases exammed. The quantities of urine employed varied considerably in different cases, but the majority of the specimens had a volume of some 200 to 400 C.C. SUMMARY OF THE RESULTS OF THE EXAMINATION OF THE URINE OF 126 INDIVIDUALS FOR H^MATOPORPHYRIN BY THE LEAD AND BARIUM METHODS. ai CO CO <a a m a O >, c u to •A u -a I <»-. o o u o o <a g-d o . u 3 truiT ined o . Diseases. .Q Diseases. 3S S a Ci and. tra 0 Spec obta 0 3 fl and . tra 0 Spec obta 1—t $■ 'a ^^ '3 w a 'o W o o H O o o < Gout, 5 2 2 1 Wasting in a child, . 1 0 1 0 Acute and Sub-acute Emphysema, with Con- gested Liver, . Rheumatism, . 23 4 16 3 1 0 1 0 Chorea, 27 2 16 9 Exophthalmic Goitre, 1 0 0 1 Tubercular Affections, 8 2 6 0 Perityphlitis, Herpes Zoster, . 1 0 0 1 Lobar Pneumonia, 4 2 0 2 1 0 0 1 Pleurisy, . 6 0 5 1 Broncho-Pneumonia, . 1 0 0 1 Cirrhosis Hepatitis, . 1 0 0 1 Epilepsy, . 2 0 0 2 Enteric Fever, . 1 0 1 0 Habit Chorea, . 1 0 0 1 Erythema Marginatum, 1 0 1 0 Thrombosis of Veins, . 1 0 0 1 Erythema Nodosum, . 4 0 2 2 Influenza, . 1 0 0 1 Febricula, . 1 0 1 0 Asthma, 1 0 0 1 Tonsillitis, 1 0 1 0 Bronchitis, 1 0 0 1 Purpura Simplex, 1 0 1 0 Valvular Disease, 2 0 0 2 Parametritis, 2 0 1 1 Tubal Nephritis, 2 0 0 2 Infantile Paralysis, Diabetes Mellitus, 2 0 0 2 with Cystitis,. 1 0 1 0 Hemiplegia, Anremia from Intest- 1 0 0 1 Empyema, . . . 2 0 1 1 Hysteria, . 2 0 1 1 inal Hemorrhage, . 1 0 0 1 Chlorosis, . Albuminuria in a chUd, 5 0 3 2 Healthy Persons, 8 0 2 6 1 0 1 0 Raynaud's Disease, 1 0 1 0 126 12 65 49