The role of cholesterol in atherosclerosis : new therapeutic opportunities / editors, Scott M. Grundy, M.D., Alexander G. Bearn, M.D.

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About this work


949 *ins=sl;bn=stax;ov=Philadelphia : Hanley & Belfus, Inc., [1988]

Physical description

ix, 261 pages : illustrations ; 24 cm.


"Merck Sharp & Dohme International Medical Advisory Council, New Milton, Hampshire, England, July 13-14, 1987."
Copy 1. Donor: Family of Martin Roth.


Opening remarks / Alexander G. Bearn -- Pathogenesis of atherosclerosis: recent concepts / Ramzi S. Cotran, J. Michael Munro -- Chronology of cholesterol synthesis / Konrad E. Bloch -- HMG-CoA reductase inhibitors / Eve E. Slater, Alfred W. Alberts, Robert L. Smith -- Worldwide clinical experience with Lovastatin/Simvastatin / Federico Moncloa -- Experience with Lovastatin: studies on mechanisms of action / Scott M. Grundy -- Use of hypolipidemic strategies to halt atherosclerosis: evidence for alteration in clinical course / Peter H. Stone, Frank M. Sacks, Thomas W. Smith -- Overview of quantitative coronary angiographic techniques: morphology, densitometry and standardization of acquisition / Johan H.C. Reiber -- Physician attitudes toward elevated lipid levels: an international perspective / C. Boyd Clarke -- Coronary heart disease: differences in the occurrence between populations and changing trends within populations; relationship to serum cholesterol levels / Kalevi Pyorala -- Desirable plasma lipid and lipoprotein levels in adults / Barry Lewis -- The 1984 National Institutes of Health Consensus Report on cholesterol in light of the understanding of lipoproteins and coronary heart disease in 1987 / Robert W. Mahley -- Atherosclerosis and lipid metabolism in the Japanese / Hiroo Imura, Kinsuke Tsuda -- Roundtable 1: worldwide prevalence of atherosclerosis: differences and similarities -- Roundtable 2: attitudes toward cholesterol reduction -- The U.S. National Cholesterol Education Program: raising health professional and public awareness about the importance of lowering high blood cholesterol / James I. Cleeman, Claude Lenfant -- Roundtable 3: medical and economic implications of Lovastatin -- Future approaches to therapy for dyslipidemia / Scott M. Grundy -- Roundtable 4: future areas of clinical and scientific opportunity: genetic predisposition/DNA probes.

Bibliographic information

Includes bibliographical references and index.



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