Fungal genetics / J.R.S. Fincham and P.R. Day.

  • John Fincham
Date:
[1963]
Catalogue details

Licence: Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)

Credit: Fungal genetics / J.R.S. Fincham and P.R. Day. Source: Wellcome Collection.

    9/334 page V
    CONTENTS 8 THE BIOCHEMICAL ANALYSIS OF GENE FUNCTION 163 The biochemical basis of auxotrophy 163 : Single versus multiple growth requirements 163 ; Information from auxotrophs on biosynthetic pathways 164; Accumulation of intermediates and absence of enzymes as further evidence for the position of metabolic blocks 165; Unexplained growth requirements 168; Multiple effects of simple metabolic lesions 170 The nature of genetically determined changes in enzyme activities 171 : Protein structure 172 ; Complete and partial losses of enzyme function 173 ; Conditional enzyme activity in mutants 175 ; Abnormal enzyme activity in partial revertants 177; Altered enzymes in 'leaky' mutants 178 ; Naturally occurring cryptic enzyme differences 179 The specificity of genetic control ofprotein structure 179 : Suppressor mutations 181 ; Quantitative effects 183 ; Complementary action of alleles in enzyme formation 184 Kinds of gene action 188 9 COMPARATIVE GENETICS AND PHYSIOLOGY OF MATING TYPE AND SEXUAL DEVELOPMENT 192 Sex and mating type controls 192 : Sexual dimorphism 193 ; Heterothallism : two allele systems 194; Multiple allelomorph heterothallism, bipolar and tetrapolar systems 197 ; Structure of the A locus in tetrapolar species 199; Mutation of the mating type loci in tetrapolar species 201 ; Secondary homothallism 203 Developmental controls and possible origins of heterothallism 206 : Glomerella cingulata 206; Sordaria fimicola 201 \ Sordaria macrospora 209 Physiology of mating type determination 210 : Hormonal controls 210; Agglutination 212; Multiple allelomorph control 213 Genetic control of heterocaryon formation 215 10 EXTRA-NUCLEAR INHERITANCE 217 Continuous cytoplasmic variation 218 Discontinuous cytoplasmic variation 220: Petite colony yeast 220; Neurospora—poky 223 ; Cytoplasmic differences between Neurospora species 225 ; Other examples of gene-cytoplasm interaction 227 ; Cytoplasmic inheritance in the Basidiomycetes 229 ; Suppressive systems 231 Possible explanations of extra-nuclear heredity 234: Evidence for the particulate nature of cytoplasmic determinants 234; Models based on self-perpetuating metabolic systems 235 ; Criteria for distinguishing between different models 237 11 GENETICS OF PATHOGENICITY 239 The genetical basis of physiologic specialization 240 Origin of physiologic races 245 : Phytophthora infestans 247; The smut fungi 248 ; The rusts 249 The basis of physiologic specialization 253 1
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