Intra-ocular injections of solutions of various antiseptic substances : an experimental inquiry / by G. E. de Schweinitz.

  • De Schweinitz, G. E. (George Edmund), 1858-1938.
Date:
1893
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Credit: Intra-ocular injections of solutions of various antiseptic substances : an experimental inquiry / by G. E. de Schweinitz. Source: Wellcome Collection.

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    mechanism of retinal detachment and the produc- tion of proliferating retinitis. Researches of the third class have been conducted chiefly to test the therapeutic value of the injection of antiseptic fluids directly into the vitreous of an inflamed eye, for example, one suffering from hya- litis, or from sympathetic ophthalmitis; or to try their efiicacy in preventing an inflammation of this character after the eye has been exposed to the influences likely to produce it. Abadie,^ in 1890, suggested the propriety of inject- ing 2 drops of a solution of sublimate, 1 to 1000, into a wounded eye, causing sympathetic ophthalmitis of the other eye, which in turn should also be treated with a similar injection directly into the vitreous humor. According to him, these injections were of use in checking and ameliorating the inflam- matory process. Subsequently he published^ three cases of sympathetic ophthalmitis cured by intra- ocular injections of corrosive sublimate, the strength of the injections being in two instances, 1 to 1000, and in one, 1 to 500. In the discussion of a paper communicated by Darier, Abadie's Chief of Clinic, to the French Society of Ophthalmology, on the 8th of May, 1891,* concerning sub-conjunctival injections of sublimate in ocular therapeutics, the question of intra-ocular injections of the same drug received attention, Wecker regarding the transition from intra-ocular to sub conjunctival injections as a decided advance, and doubting the efficacy of the former method of administration. In the close of the discussion, Abadie expressed himself as willing to abandon the intra-ocular injections of sublimate for sub-conjunc- tival injections, provided it is demonstrated that 6 Pathog^nie et nouveau Traitement de rOphthalmie Sympathet- Ique. Annales d'Oculistiqiie, Vol. ciii, 1890, p. 183. 'i Nouveaux cas d'Ophthalmie Sympattiique, Gu^ri par les Injec- tions intra-oculaires de Sublime. Annales d'Oculistique, Vol. civ, 1890, p. 229. 8 Des Injections sous—conjunctivales de Sublim6 en Th^rapeutique oculaire, Arch. d'Ophthal. Vol. xi, 1891 p. 449.