A type of reaction by which sodium carbonate and hydrochloric acid may be formed in the animal organism.

  • Osborne, Thomas B. (Thomas Burr), 1859-1929.
Date:
[1900]
Catalogue details

Licence: In copyright

Credit: A type of reaction by which sodium carbonate and hydrochloric acid may be formed in the animal organism. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    442 CONNECTICUT EXPERIMENT STATION REPORT, I9OO. insoluble in dilute sodium chloride solution, was largely soluble in pure water, as well as in strong sodium chloride brine, yield- ing solutions acid to litmus and to phenolphthalein; to neutra- lize one gram to the latter indicator, 1.9 cc. of decinormal potas- sium hydrate solution being required. Fifteen grams of this preparation were treated with freshly boiled water and 28.5 cc. of decinormal potassium hydrate solution, diluted with much water, were added. The edestin, which separated completely from the solution, was then filtered out, washed with water and filtrate and washings evaporated on a water-bath. The residue was dried at no° and analyzed with the following results: Gram. Organic matter 0.0222 Inorganic matter 0.2123 Total residue 0.2345 The inorganic residue contained: Gram. Potassium chloride 0.1994 Potassium sulphate 0.0153 The potassium added was equivalent to 0.2127 gram of potassium chloride, so that over 93 per cent, of the potassium added was recovered as chloride. From this analysis we find that with the 15 grams of edestin, equal to 13.5 grams dried at no°, 0.0976 gram of hydrochloric acid or 0.072 per cent, of the protein had been precipitated. Corresponding to this quantity of hydrochloric acid, 0.1417 gram of sodium carbonate must have been produced in the salt solution by the carbonic acid. It seems probable that by a similar reaction both sodium carbonate and hydrochloride acid may be formed from sodium chloride in the organism, since there is always sodium chloride and protein matter present where carbonic acid is produced in the tissues.* 4 * Cf. Schulz: Pfliiger’s Archiv. 27, 454.