Gout and its relations to diseases of the liver and kidneys / by Robson Roose.

  • Roose, Robson, 1848-1905.
Date:
1885
Catalogue details

Licence: Public Domain Mark

Credit: Gout and its relations to diseases of the liver and kidneys / by Robson Roose. Source: Wellcome Collection.

Provider: This material has been provided by Royal College of Physicians, London. The original may be consulted at Royal College of Physicians, London.

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    becomes completely dissolved, and the cartilage is almost or quite normal in structure. Wherever the de- posit is found, the microscopic appearances are similar to those presented by the affected cartilage. If acetic acid be added, rhomboidal crystals of uric acid will appear. The tophi, or chalk-stones, often seen in the neighbourhood of the joints, consist of sodium urate, with a little urate and phosphate of calcium. They differ entirely from the bony nodosities of chronic articular rheumatism. Their most favourite seats are the joints of the hands and feet and external ear. After some time, the skin covering them often becomes thin and brittle, and particles of chalk-like matter are found to cover the surface. In some cases the chalk- stones set up considerable irritation, and abscesses form, which, on bursting, leave ulcers. The discharges from such abscesses are milky and paste-like, and consist of sodium urate, pus, and debris. The ulcers are indolent; the granulations are spongy, scanty, and yellowish ; and the bases and edges are studded with particles of mortar-like material. Such ulcers often remain without change for long periods, and are apt to re-open after cicatrization. In order to complete this sketch of the morbid anatomy of gout, allusion must be made to the