Gout and its relations to diseases of the liver and kidneys / by Robson Roose.

  • Roose, Robson, 1848-1905.
Date:
1885
Catalogue details

Licence: Public Domain Mark

Credit: Gout and its relations to diseases of the liver and kidneys / by Robson Roose. Source: Wellcome Collection.

Provider: This material has been provided by Royal College of Physicians, London. The original may be consulted at Royal College of Physicians, London.

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    twenty-four hours. The blood-serum can easily be shown to contain excess of uric acid. In the intervals the condition of the urine varies, but there are often deposits of urates and of crystalline uric acid. In chronic gout the excretion of uric acid is for the most part diminished, but from time to time there are crystalline and amorphous deposits containing this substance. Oxalate of lime is often found, tube-casts and albumen are by no means rare, and sugar is occasionally present. Having thus briefly referred to the state of the blood and urine, the morbid changes in gouty subjects constitute the next point of importance. They are well marked in severe and chronic cases, and are for the most part the direct consequences of the excess of uric acid in the blood. Certain tissues and organs are the seat of deposits consisting of sodium urate, and a careful study of these changes throws much light upon the nature of the disease. The existence of the so- called “chalk-stones” has been recognised from a very early period, but they were regarded as associated only with very severe cases of gout. A closer in- vestigation has shown that even a very slight attack leaves behind it marked changes in the structure of the joints, and that these changes generally remain,