Toxic shock syndrome toxin

  • K R Acharya
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Toxic shock syndrome toxin. K R Acharya. Attribution 4.0 International (CC BY 4.0). Source: Wellcome Collection.

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A molecular model of the Toxic shock syndrome toxin-1 (TSST-1). This bacterial protein superantigen is produced by Staphlococcus aureus and invokes an extremely strong immune response. It cross links MHC class II molecules with T-cell receptors to bring about cytokine production in T-cells which leads on to various shock related symptoms such as a drop in blood pressure, vomiting, diarrhoea, toxic shock and fever.


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