Find thousands of books, manuscripts, visual materials and unpublished archives from our collections, many of them with free online access.

Prostate cancer cells treated with nano sized drug carriers

  • Dr Khuloud T. Al-Jamal
  • Digital Images
  • Online

Available online

view Prostate cancer cells treated with nano sized drug carriers

Licence

Attribution 4.0 International (CC BY 4.0)
You can use this work for any purpose, including commercial uses, without restriction under copyright law. You should also provide attribution to the original work, source and licence.
Creative Commons Attribution (CC BY 4.0) terms and conditions https://creativecommons.org/licenses/by/4.0
Credit: Prostate cancer cells treated with nano sized drug carriers. Khuloud T. Al-Jamal & Houmam Kafa. Attribution 4.0 International (CC BY 4.0)

Selected images from this work


About this work

Description

3-dimensional reconstruction of a hollow multi-cellular prostate tumour spheroid (cluster of cells) imaged by confocal microscopy. Cell nuclei in the spheroid are stained with the fluorescent dye propidium iodide (red). Dendrimer nano-carriers (blue) are made of hyber-branched poly-L-lysine polymer and carry the cytotoxic drug doxorubicin (black and red beads inside the dendrimer). They were modelled in imaging software and then artificially inserted into the tumour in this image to give an idea of how they would interact with it. Doxorubicin encapsulated inside the dendrimer is able to penetrate deeper into the spheroid better killing the prostate tumour cells. Diameter of the spheroid is approximately 250 micrometers.


Permanent link