Trimeric G protein, complex with RGS4, model
- T.Blundell & N Campillo
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Description
Molecular model of G alpha (a trimeric G protein)
in complex with RGS4 (regulator of G-protein
signalling, PDB code:1agr), ribbon diagram. G
alpha is shown in green with the switch regions
I and II in red. RGS4 is shown in blue. The
trimeric guanine nucleotide-binding proteins are
involved as transducers in various transmembrane
signalling systems. The G alpha (s) protein is
involved in hormonal regulation of adenylate
cyclase: it activates the cyclase in response to
beta-adrenergic stimuli, and is regulated by RGS4.